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Sperm DNA Fragmentation

Lab Visit
Rs. 4,500
Sample: Semen
Turnaround Time: After 5 Days
About Test:

Sperm DNA Fragmentation:

 

The sperm DNA fragmentation test is used to calculate the per cent of DNA that is fragmented. that occurs in the sperm within a sample of semen produced by a male. DNA is a very important part of the sperm. It passes on your characteristics to a newborn child. There is always some breaking down of DNA during sperm production. However, the amount cannot be too high.

Sperm DNA fragmentation refers to either a single-stranded or double-stranded break in the DNA of the sperm. In the sperm, there is an inability to repair these breaks and hence the DNA damage persists. This DNA damage can negatively affect conception and cause subfertility.

 

 

Medical condition:

Infertility\Subfertility:

Test preparation:

Abstinence of 4 days

Sample can be frozen and transported in dry ice

 

About Disease

What is DNA?

DNA is genetic material. It transfers our characteristics to our children in the form of genes It is extremely complex and made up of several proteins that represent our traits. These are passed on to our children during fertilization. However, if the DNA in the reproductive cells (sperm and ova) are fragmented, conceiving a child can be harder.

What increases the risk DNA fragmentation?

In addition to natural fragmentation, stress caused by free elements within the body can lead to a breaking down of DNA in the sperm. This is related to: Stress Fever or inflammation ,Excess smoking and alcohol use ,Recreational drug use, Using body-building supplements , Sexually transmitted infections

Any Other Information

Sperm DNA fragmentation should be done along with the Sperm Mitochondrial membrane potential test

 

FAQs about Sperm DNA Fragmentation

What are the causes of increased Sperm DNA fragmentation?:

1. Oxidative stress: Smoking, excessive alcohol, Obesity, High BMI, Diabetes, Drugs., varicocele, advanced age, radiation

2.Defective Chromatin Maturation

3.Defective apoptosis: Sperm which were designed to be eliminated is not due to a defect in apoptosis

What are the effects of an increased Sperm DNA fragmentation?

1.Less likely to conceive naturally

2.Increased risk of recurrent pregnancy loss

3.Cant affect the outcome of assisted reproduction techniques(ART)

What is the procedure of the sperm DNA fragmentation test?

A semen sample has to be produced by the male in our centre after 2-3 days of abstinence from intercourse or ejaculation.

This sample is put through a centrifugation process and then processed for flow cytometry

Judging by the amount of Fragmented DNA on the flow cytometer machine, a percentage DFI is given.

Anything above 20-25% DFI is considered to have an impact on fertility

What is normal sperm DNA fragmentation?

Anything above 20-25% DFI is considered to have an impact on fertility

DFI: Under 15% is recommended

 

 

Can you improve sperm DNA fragmentation?

There are certain steps to be taken post an abnormal test.

1.Treat the underlying cause. For example, varicocele can increase the DFI by 5%. Treatment of varicocele will therefore reduce the DFI. Or treating an infection with an antibiotic

2.Lifestyle modification: Quitting smoking, reducing alcohol intake. Regular exercise, reducing the BMI

3.Use of ICSI(the technique that the doctors will use for treatment).

4.Recurrent ejaculation

 

 

What are the Indications for Sperm DNA Fragmentation testing?

• Unexplained or idiopathic male infertility

• Recurrent pregnancy loss

• Clinical varicocele

• Lifestyle risk factors

• Before or after the failure of ART–IUI, IVF, ICSI

• Recurrent pregnancy loss after ICSI

• Sperm freezing

Sperm DNA Fragmentation Near Me

Find a Sperm DNA Fragmentation Lab Near You in Mumbai, Thane and Navi Mumbai

Branch Address Lab Timing Contact Details Contact Email
Malad SRL Dr. Avinash Phadke LabsIndraprasth Chs, 581, Shop No 02, Building Number 3, Ground Floor, Near Ashoka Hospital, Malad East, Mumbai -400097 Monday to Saturday: 08 am to 06 pm | Sunday: 08 am to 03 pm 7498275795 / 9271535060 care@phadkelabs.com
Kamothe SRL Dr. Avinash Phadke LabsPratik Gardens, Shop Number 33, Plot No. 153 -165, Sect. No. 34, Kamothe, Navi Mumbai - 410209 Mon to Sat: 08 am to 02 pm | Sunday closed 9167450036 care@phadkelabs.com
Kharghar SRL Dr. Avinash Phadke LabsPlot No. 3, Gokul Dham, Sector 35D, Kharghar, Navi Mumbai - 410210 Mon to Sat: 08 am to 02 pm | Sunday closed 9167400135 care@phadkelabs.com
Khanda Colony, Panvel SRL Dr. Avinash Phadke LabsTulsi harmony, Shop no. 20, plot no. 26-27, Sector 1. Khanda Colony, New Panvel West, Navi Mumbai - 410206 Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 12 pm 8291097310 care@phadkelabs.com
Mahalaxmi SRL Dr. Avinash Phadke LabsShop No. 1/A, Ground Floor, Sagar Villa Building, 38 Bhulabai Desai Road, Mumbai - 400026 Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 05 pm 9222200935 care@phadkelabs.com
Dadar SRL Dr. Avinash Phadke LabsGround Floor, Udyam, Ranade road, Next to Oven Fresh Cake Shop, Shivaji Park, Dadar West, Mumbai - 400028 Mon to Sat: 07.30 am to 03.00 pm | Sunday: 08.00 am to 03.00 pm 022 61367900 / 022 62356500 care@phadkelabs.com
Mahim Camlin Centre SRL Dr. Avinash Phadke Labs210 - Rambaug, Ground Floor, L.J. Road, Next to Bank of Baroda, Mahim West, Mumbai - 400016 Mon to Sat: 07.30 am to 03.00 pm | Sunday: 08.00 am to 03.00 pm 022 61365301 / 022 61365302 care@phadkelabs.com
Andheri SRL Dr. Avinash Phadke LabsR.N.A Arcade, Shop No 19 / 20 , 04th Cross Lane, Opp Oriental Bank, Lokhandwala Complex, Andheri West, Mumbai - 400053 Mon to Sat: 08.00 am to 08.00 pm | Sunday: 08:00 am to 01:00 pm 7304472887 / 7506112559 / 022 61364100 / 022 61364102 care@phadkelabs.com
Sion Anoop Pathology Lab29-B, Mira Mansion, Opposite Punjab National Bank, Sion circle, Sion West, Mumbai - 400022 Mon to Sat: 08.00 am to 02.00 pm | Sunday: 08.00 to 02.00 pm 022 24071550 care@phadkelabs.com
Chembur Chheda Nagar Collection centreSri Subramanian Samaj, Temple complex, Chheda Nagar, Chembur West, Mumbai - 400089 Mon to Sat - 08.00 am to 02.00 pm | Sunday closed 8655522531 / 022 25250458 care@phadkelabs.com
Mulund (West) SRL Dr. Avinash Phadke LabsSumati Building, Ground Floor, Behind Saraswat Co-Operative Bank opposite Kirti Mahal Hotel, MG Road, Mulund West, Mumbai- 400080 Mon to Sat - 08 am to 02 pm | Sunday closed  022 25623742 care@phadkelabs.com
Mulund (East) SRL Dr. Avinash Phadke LabsAseem Anand bldg, Ground Floor, near Bhavani Bank, Gopal Krishna Gokhale Rd, Mulund East, Mumbai- 400081 Mon to Sat: 08 am to 02 pm | Sunday closed 022 21632568 / 022 25655159 care@phadkelabs.com
Wadala SRL Dr. Avinash Phadke LabsDosti Estate, New Shop No. C15, Ground Floor, Plot No. 141C, Neptune, Antop Hill, S. M. Road, Wadala East, Mumbai- 400037 Mon to Sat: 08 am to 05 pm | Sunday closed 9967293710 care@phadkelabs.com
Matunga (East) Maheshwari ClinicMatunga Clinic & Hopsital, Dr Ambedkar rd, 541/D, C.G Niketan, Matunga East, Mumbai 400019. Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 02 pm 9664079093 / 8655463378 / 9222244664 care@phadkelabs.com
Matunga (West) SRL Dr. Avinash Phadke LabsShop Number 6, Opp Karnataka Sangha, Mogul Lane, Matunga West, Mumbai, Maharashtra - 400016 Mon to Sat: 08 am to 02 pm | Sunday closed 093200 49588 care@phadkelabs.com
Bandra West Harmony Clinic302, Silver Pearl, 3rd Floor, Waterfield Road, Opposite IDFC Bank, Lane opposite Lavender / China Gate, Bandra West, Mumbai - 400050 Mon to Sat: 08 am to 09 pm | Sunday closed 9820551144 / 8779967799 care@phadkelabs.com
Nerul SRL Dr. Avinash Phadke LabsShop no 29, Ameya CHS (Wadhava Residency), Plot no 24-29, Sector -4 Nerul West, Navi Mumbai - 400706. Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm 9967236088 srldiagnostocs.nerul04@gmail.com
Sanpada SRL Dr. Avinash Phadke LabsShop No 16, Millennium Shopping Complex, Sector -9, Sanpada, Navi Mumbai - 400705. Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm 9768517646 maliksarfaraz8898@gmail.com
Belapur SRL Dr. Avinash Phadke LabsShop No 6, Sankula Tower, Sector 8-B, CBD Belapur, Navi Mumbai – 400614 Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm 8097746052 care@phadkelabs.com
Airoli SRL Dr. Avinash Phadke LabsBungalow No C-8, Ground Floor, Sector 4, oppo. Airoli fire brigade , Airoli, Navi Mumbai - 400708 Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm 9222583868 care@phadkelabs.com
Vile Parle SRL Dr. Avinash Phadke LabsDR. SUCHITA TODI (VILE -PARLE), GR FLR, SHREENATH BLDG, BAJAJ ROAD, OPP. TITAN CERAMICS, NEAR AMRUT BAUG, VILE PARLE WEST, MUMBAI: 400056 , MAHARASHTRA 7.30 am to 7.30 pm (Mon to Sat) Sun: 7.30 am to 2.30 pm 9819188053 / 9833885537 care@phadkelabs.com
Branch: Malad
Address: Indraprasth Chs, 581, Shop No 02, Building Number 3, Ground Floor, Near Ashoka Hospital, Malad East, Mumbai -400097
Lab Timing: Monday to Saturday: 08 am to 06 pm | Sunday: 08 am to 03 pm
Contact Details: 7498275795 / 9271535060
Contact Email: care@phadkelabs.com
Branch: Kamothe
Address: Pratik Gardens, Shop Number 33, Plot No. 153 -165, Sect. No. 34, Kamothe, Navi Mumbai - 410209
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday closed
Contact Details: 9167450036
Contact Email: care@phadkelabs.com
Branch: Kharghar
Address: Plot No. 3, Gokul Dham, Sector 35D, Kharghar, Navi Mumbai - 410210
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday closed
Contact Details: 9167400135
Contact Email: care@phadkelabs.com
Address: Tulsi harmony, Shop no. 20, plot no. 26-27, Sector 1. Khanda Colony, New Panvel West, Navi Mumbai - 410206
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 12 pm
Contact Details: 8291097310
Contact Email: care@phadkelabs.com
Branch: Mahalaxmi
Address: Shop No. 1/A, Ground Floor, Sagar Villa Building, 38 Bhulabai Desai Road, Mumbai - 400026
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 05 pm
Contact Details: 9222200935
Contact Email: care@phadkelabs.com
Branch: Dadar
Address: Ground Floor, Udyam, Ranade road, Next to Oven Fresh Cake Shop, Shivaji Park, Dadar West, Mumbai - 400028
Lab Timing: Mon to Sat: 07.30 am to 03.00 pm | Sunday: 08.00 am to 03.00 pm
Contact Details: 022 61367900 / 022 62356500
Contact Email: care@phadkelabs.com
Address: 210 - Rambaug, Ground Floor, L.J. Road, Next to Bank of Baroda, Mahim West, Mumbai - 400016
Lab Timing: Mon to Sat: 07.30 am to 03.00 pm | Sunday: 08.00 am to 03.00 pm
Contact Details: 022 61365301 / 022 61365302
Contact Email: care@phadkelabs.com
Branch: Andheri
Address: R.N.A Arcade, Shop No 19 / 20 , 04th Cross Lane, Opp Oriental Bank, Lokhandwala Complex, Andheri West, Mumbai - 400053
Lab Timing: Mon to Sat: 08.00 am to 08.00 pm | Sunday: 08:00 am to 01:00 pm
Contact Email: care@phadkelabs.com
Branch: Sion
Address: 29-B, Mira Mansion, Opposite Punjab National Bank, Sion circle, Sion West, Mumbai - 400022
Lab Timing: Mon to Sat: 08.00 am to 02.00 pm | Sunday: 08.00 to 02.00 pm
Contact Details: 022 24071550
Contact Email: care@phadkelabs.com
Branch: Chembur
Address: Sri Subramanian Samaj, Temple complex, Chheda Nagar, Chembur West, Mumbai - 400089
Lab Timing: Mon to Sat - 08.00 am to 02.00 pm | Sunday closed
Contact Details: 8655522531 / 022 25250458
Contact Email: care@phadkelabs.com
Address: Sumati Building, Ground Floor, Behind Saraswat Co-Operative Bank opposite Kirti Mahal Hotel, MG Road, Mulund West, Mumbai- 400080
Lab Timing: Mon to Sat - 08 am to 02 pm | Sunday closed
Contact Details:  022 25623742
Contact Email: care@phadkelabs.com
Address: Aseem Anand bldg, Ground Floor, near Bhavani Bank, Gopal Krishna Gokhale Rd, Mulund East, Mumbai- 400081
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday closed
Contact Details: 022 21632568 / 022 25655159
Contact Email: care@phadkelabs.com
Branch: Wadala
Address: Dosti Estate, New Shop No. C15, Ground Floor, Plot No. 141C, Neptune, Antop Hill, S. M. Road, Wadala East, Mumbai- 400037
Lab Timing: Mon to Sat: 08 am to 05 pm | Sunday closed
Contact Details: 9967293710
Contact Email: care@phadkelabs.com
Address: Matunga Clinic & Hopsital, Dr Ambedkar rd, 541/D, C.G Niketan, Matunga East, Mumbai 400019.
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday: 08 am to 02 pm
Contact Details: 9664079093 / 8655463378 / 9222244664
Contact Email: care@phadkelabs.com
Address: Shop Number 6, Opp Karnataka Sangha, Mogul Lane, Matunga West, Mumbai, Maharashtra - 400016
Lab Timing: Mon to Sat: 08 am to 02 pm | Sunday closed
Contact Details: 093200 49588
Contact Email: care@phadkelabs.com
Branch: Bandra West
Address: 302, Silver Pearl, 3rd Floor, Waterfield Road, Opposite IDFC Bank, Lane opposite Lavender / China Gate, Bandra West, Mumbai - 400050
Lab Timing: Mon to Sat: 08 am to 09 pm | Sunday closed
Contact Details: 9820551144 / 8779967799
Contact Email: care@phadkelabs.com
Branch: Nerul
Address: Shop no 29, Ameya CHS (Wadhava Residency), Plot no 24-29, Sector -4 Nerul West, Navi Mumbai - 400706.
Lab Timing: Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm
Contact Details: 9967236088
Branch: Sanpada
Address: Shop No 16, Millennium Shopping Complex, Sector -9, Sanpada, Navi Mumbai - 400705.
Lab Timing: Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm
Contact Details: 9768517646
Branch: Belapur
Address: Shop No 6, Sankula Tower, Sector 8-B, CBD Belapur, Navi Mumbai – 400614
Lab Timing: Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm
Contact Details: 8097746052
Contact Email: care@phadkelabs.com
Branch: Airoli
Address: Bungalow No C-8, Ground Floor, Sector 4, oppo. Airoli fire brigade , Airoli, Navi Mumbai - 400708
Lab Timing: Monday to Saturday: 07 am to 07 pm | Sunday: 07 am to 01 pm
Contact Details: 9222583868
Contact Email: care@phadkelabs.com
Branch: Vile Parle
Address: DR. SUCHITA TODI (VILE -PARLE), GR FLR, SHREENATH BLDG, BAJAJ ROAD, OPP. TITAN CERAMICS, NEAR AMRUT BAUG, VILE PARLE WEST, MUMBAI: 400056 , MAHARASHTRA
Lab Timing: 7.30 am to 7.30 pm (Mon to Sat) Sun: 7.30 am to 2.30 pm
Contact Details: 9819188053 / 9833885537
Contact Email: care@phadkelabs.com
Sperm DNA Fragmentation
Test Code : SPERMD
Rs. 4,500
Sample: Semen
Turnaround Time: After 5 Days

Visit charges of Rs. 100 would be applicable for Home visits booked

  • In-case of a test that requires 2 visits, each visit will be charged Rs. 100
  • Sunday visits will be taken subject to availability of time slots.
  • Home visit charges and Sunday rates are applicable for Mumbai, Navi Mumbai & Thane district
  • Terms and Conditions Apply

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