WHOLE BLOOD / BONE MARROW (EDTA / HEPARIN 3 OR 4 UNSTAINED AIR DRIED SLIDES)
Report turn around time
After 3 days
Plasma cell neoplasms primarily involve the bone marrow. They predominantly occur in the elderly and can present with lytic bone lesions, kidney involvement and anemia. A set of criteria, that include evaluation of serum creatinine, serum calcium, a complete blood count with peripheral smear examination and monoclonal protein detection in the peripheral blood or evaluation of plasma cell clonality, need to be fulfilled for the diagnosis. Plasma cell clonality can be assessed indirectly by immunofixation or directly by flow cytometry. Flow cytometry has the advantage of identifying even the smallest abnormal populations even when no monoclonal protein is detected on electrophoresis.